IL1RL2 antibody

Catalog No. ABIN7115403

This anti-IL1RL2 antibody is a Rabbit Polyclonal antibody detecting IL1RL2 in WB, ELISA and FACS. Suitable for Human.

Quick Overview for IL1RL2 antibody (ABIN7115403)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-IL1RL2 Antibody

Purpose: IL1RL2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interleukin 1 receptor-like 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Alternative Name: IL1RL2

Background:

Synonyms: Interleukin-1 receptor-like 2|IL-36 receptor (IL-36R)|Interleukin-1 receptor-related protein 2 (IL-1Rrp2, IL1R-rp2)|IL1RL2|IL1RRP2

Background: Receptor for interleukin-36(IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways(By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response, it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Molecular Weight: 65 kDa

Gene ID: 8808

UniProt: Q9HB29